Phoenix Bio

R&D OVERVIEW

R&D OVERVIEW

Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice

    Tateno, C. Kawase, Y. Tobita, Y. Hamamura, S. Ohshita, H. Yokomichi, H. Sanada, H. Kakuni, M. Shiota, A. Kojima, Y. Ishida, Y. Shitara, H. Wada, N. A. Tateishi, H. Sudoh, M. Nagatsuka, S. Jishage, K. Kohara, M.

    PLoS One. 2015 Nov 4;10(11):e0142145. doi: 10.1371/journal.pone.0142145. eCollection 2015.

    Efficient engraftmentof human iPS cell-derived hepatocyte-like cells in uPA/SCID mice by overexpression of FNK, a Bcl-xmutant gene

      Nagamoto, Y. Takayama, K. Tashiro, K. Tateno, C. Sakurai, F. Tachibana, M. Kawabata, K. Ikeda, K. Tanaka, Y. Mizuguchi, H.
      Cell Transplant. 2015;24(6):1127-38.

      Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes.

        Tachibana A, Tateno C, Yoshizato K.
        Xenotransplantation. 2013 Jul;20(4):227-38.

        Transplantation of engineered chimeric liver with autologous hepatocytes and xenobiotic scaffold

          Hata T, Uemoto S, Fujimoto Y, Murakami T, Tateno C, Yoshizato K, Kobayashi E.
          Ann Surg. 2013 Mar;257(3):542-7.

          Morphological and microarray analyses of human hepatocytes from xenogeneic host livers

            Chise Tateno, Fuyuki Miya, Kenjiro Wake, Miho Kataoka, Yuji Ishida, Chihiro Yamasaki, Ami Yanagi, Masakazu Kakuni, Eddie Wisse, Fons Verheyen, Kouji Inoue, Kota Sato, Atsushi Kudo, Shigeki Arii, Toshiyuki Itamoto, Toshimasa Asahara, Tatsuhiko Tsunoda and Katsutoshi Yoshizato
            Lab Invest. 2013 Jan;93(1):54-71.

            A novel animal model for in vivo study of liver cancer metastasis.

              Fujiwara S, Fujioka H, Tateno C, Taniguchi K, Ito M, Ohishi H, Utoh R, Ishibashi H, Kanematsu T, Yoshizato K.
              World J Gastroenterol. 2012 Aug 7;18(29):3875-82.

              Liver tissue engineering utilizing hepatocytes propagated in mouse livers in vivo.

                Ohashi K, Tatsumi K, Tateno C, Kataoka M, Utoh R, Yoshizato K, Okano T.
                Cell Transplant. 2012;21(2-3):429-36.

                Human hepatocyte propagation system in the mouse livers: functional maintenance of the production of coagulation and anticoagulation factors.

                  Tatsumi K, Ohashi K, Tateno C, Yoshizato K, Yoshioka A, Shima M, Okano T.
                  Cell Transplant. 2012;21(2-3):437-45.

                  Growth hormone-dependent pathogenesis of human hepatic steatosis in a novel mouse model bearing a human hepatocyte-repopulated liver.

                    Tateno C, Kataoka M, Utoh R, Tachibana A, Itamoto T, Asahara T, Miya F, Tsunoda T, Yoshizato K.
                    Endocrinology. 2011 Apr;152(4):1479-91.

                    Morphologic characterization of PhoenixBio (uPA+/+/SCID) humanized liver chimeric mouse model.

                      Peterson RA, Krull DL, Brown HR, de Serres M.

                      Drug Metab Lett. 2010 Aug;4(3):180-184.