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Propagation of Human Hepatocytes in uPA/SCID Mice: Producing Chimeric Mice with Humanized Liver
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Assessing the Therapeutic Potential of Lab-Made Hepatocytes
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Hepatology. 2016 Mar 25. doi: 10.1002/hep.28569
In Vitro and in Vivo Assessments of Drug-induced Hepatotoxicity and Drug Metabolism in Humans (In Japanese)
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Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound
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Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics
Sanoh, S. Ohta, S.
Biopharm Drug Dispos. 2014 Mar;35(2):71-86.
Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver
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A mouse with humanized liver as an animal model for predicting drug effects and for studying hepatic viral infection: where to next?
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