WHAT IS A PXB-MOUSE?
WHY OUR PXB-MOUSE IS THE WORLD'S MOST USED AND RENOWNED MODEL FOR DRUG DEVELOPMENT
PXB-mice are certified by our quality control criteria.
Study services with PXB-mice are only conducted with animals which have their liver repopulated with 70% human hepatocytes or greater.
The criteria for our PXB-Mouse Quality Control is as follows:
- Replacement Index [RI]：≥ 70% (RI is calculated by blood human Albumin concentration)
- Body Weight：≥ 16 g
- Age：12 – 18 weeks old at start of the study
We recommend to use animals with RI of 80 to 85%, which are the majority of our mouse stock production.
High quality is ensured by large scale production
PhoenixBio is able to provide top-notch mice from our mouse stock for your study, in which 100 PXB-mice are supplied every week.
1. Stable human albumin levels
2. Stable body weights
3. Highly humanized condition
It is observed via Microarray analysis that almost all the genes which are expressed in a normal human liver are also expressed in the PXB-Mouse liver.
Please use the link below to look up specific human gene expression levels found in our PXB-Mouse, and see if our mouse model is capable of expressing your gene of interest.