| 株式会社フェニックスバイオ

Seigo Sanoh*,a, Yuka Tamuraa, Chieri Fujinoa, Go Sugaharab, Yasumi Yoshizaneb, Ami Yanagib, Keishi Kisohb, Yuji Ishidab,c, Chise Tatenob,c, Shigeru Ohtaa,d, and Yaichiro Kotakea.

BPB Reports

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Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/31097716

Kang, J. A. Kim, S. Park, M. Park, H. J. Kim, J. H. Park, S. Hwang, J. R. Kim, Y. C. Jun Kim, Y. Cho, Y. Sun Jin, M. Park, S. G.

Nat Commun. 2019 May 16;10(1):2184. doi: 10.1038/s41467-019-10200-5.

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Changes in Bile Acid Concentrations in Chimeric Mice Transplanted with Different Replacement Indexes of Human Hepatocytes

2019/06/26

Pub Med URL https://www3.e-kenkyu.com/bpb-reports-online-journal/authors/13

Chieri Fujino,a Seigo Sanoh,*,a Yuka Tamura,a Yuji Ishida,b,c Chise Tateno,b,c Shigeru Ohta,a,d and Yaichiro Kotakea.

BPB Reports 2, 29-34 (2019)

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Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30978357

Lupberger, J. Croonenborghs, T. Roca Suarez, A. A. Van Renne, N. Juhling, F. Oudot, M. A. Virzi, A. Bandiera, S. Jamey, C. Meszaros, G. Brumaru, D. Mukherji, A. Durand, S. C. Heydmann, L. Verrier, E. R. El Saghire, H. Hamdane, N. Bartenschlager, R. Fereshetian, S. Ramberger, E. Sinha, R. Nabian, M. Everaert, C. Jovanovic, M. Mertins, P. Carr, S. A. Chayama, K. Dali-Youcef, N. Ricci, R. Bardeesy, N. M. Fujiwara, N. Gevaert, O. Zeisel, M. B. Hoshida, Y. Pochet, N. Baumert, T. F.

Gastroenterology. 2019 Apr 9. pii: S0016-5085(19)35670-7. doi: 10.1053/j.gastro.2019.04.003.

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Metabolism of Butyrylfentanyl in Fresh Human Hepatocytes: Chemical Synthesis of Authentic Metabolite Standards for Definitive Identification

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30930421

Kanamori, T. Iwata, Y. T. Segawa, H. Yamamuro, T. Kuwayama, K. Tsujikawa, K. Inoue, H.

Biol Pharm Bull. 2019;42(4):623-630. doi: 10.1248/bpb.b18-00765.

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Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29619871

Nakayama, K. Ito, S. Suzuki, M. Takubo, H. Yamazaki, H. Nomura, Y.

Xenobiotica. 2019 Apr; 49(4):404-414. doi:10.1080/00498254.2018.1460516. Epub 2018 Apr 19.

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PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30365161

Mueller, H. Lopez, A. Tropberger, P. Wildum, S. Schmaler, J. Pedersen, L. Han, X. Wang, Y. Ottosen, S. Yang, S. Young, J. A. T. Javanbakht, H.

Hepatology. 2019 Apr;69(4):1398-1411. doi: 10.1002/hep.30329. Epub 2019 Mar 1.

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HCV-induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30836093

Hamdane, N. Juhling, F. Crouchet, E. El Saghire, H. Thumann, C. Oudot, M. A. Bandiera, S. Saviano, A. Ponsolles, C. Roca Suarez, A. A. Li, S. Fujiwara, N. Ono, A. Davidson, I. Bardeesy, N. Schmidl, C. Bock, C. Schuster, C. Lupberger, J. Habersetzer, F. Doffoel, M. Piardi, T. Sommacale, D. mamura, M. Uchida, T. Ohdan, H. Aikata, H. Chayama, K. Boldanova, T. Pessaux, P. Fuchs, B. C. Hoshida, Y. Zeisel, M. B. Duong, F. H. T. Baumert, T. F.

Gastroenterology. 2019 Mar 2. pii: S0016-5085(19)32506-5. doi: 10.1053/j.gastro.2019.02.038.

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An Association Between Core Mutations in Hepatitis B Virus Genotype F1b and Hepatocellular Carcinoma in Alaskan Native People

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29893492

Hayashi, S. Khan, A. Simons, B. C. Homan, C. Matsui, T. Ogawa, K. Kawashima, K. Murakami, S. Takahashi, S. Isogawa, M. Ikeo, K. Mizokami, M. McMahon, B. J. Tanaka, Y.

Hepatology. 2019 Jan;69(1):19-33. doi: 10.1002/hep.30111. Epub 2018 Dec 10.

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Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30844328

Ishida, Y. Kakuni, M. Bang, B. R. Sugahara, G. Lau, D. T. Tateno-Mukaidani, C. Li, M. Gale, M., Jr. Saito, T.

J Interferon Cytokine Res. 2019 Mar;39(3):133-146. doi: 10.1089/jir.2018.0103.

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Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30875937

Tsuge, M. Uchida, T. Walsh, K. Ishida, Y. Tateno, C. Kumar, U. Glenn, J. S. Koh, C. Heller, T. Uprichard, S. L. Dahari, H. Chayama, K.

Viruses. 2019 Mar 15;11(3). pii: v11030263. doi: 10.3390/v11030263.

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Prediction of Human Hepatic Clearance for Cytochrome P450 Substrates via a New Culture Method Using the Collagen Vitrigel Membrane Chamber and Fresh Hepatocytes Isolated from Liver Humanized Mice

2019/06/26

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30828066

Watari, R. Kakiki, M. Yamasaki, C. Ishida, Y. Tateno, C. Kuroda, Y. Ishida, S. Kusano, K.

Biol Pharm Bull. 2019;42(3):348-353. doi: 10.1248/bpb.b18-00582.

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第46回日本毒性学会学術年会でのPXBマウス及びPXB-cells関連研究発表、ランチョンセミナー開催及びブース展示のご案内

2019/06/17

2019年6月26日(水)～6月28日(金)に開催されます第46回日本毒性学会学術年会にてPXBマウス及びPXB-cells関連の研究発表、ランチョンセミナー及びブース展示を行います。

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EASLでのPXBマウス・PXB-cells関連研究発表のご案内

2019/04/03

4月10日(水)～14日(日)にReed Messe Wien Exhibition & Congress Center(オーストリアのウィーン)で開催されますEASL The International Liver Congress 2019にて、PXBマウス・PXB-cells関連研究発表及びブース展示があります。

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Humanized Mouse Models for the Study of Hepatitis C and Host Interactions

Humanized Mouse Models for the Study of Hepatitis C and Host Interactions

Utility of Chimeric Mice with Humanized Liver for Predicting Human Pharmacokinetics in Drug Discovery: Comparison with in Vitro-in Vivo Extrapolation and Allometric Scaling

Mice with Chimeric Human Livers and Their Applications

日本核酸医薬学会第5回年会でのPXBマウス及びPXB-cells関連研究発表及びブース展示のご案内

第15回 広島肝臓プロジェクト研究センター シンポジウムでのPXBマウス及びPXBマウス関連研究発表のご案内

Study of the Metabolism of New Drugs of Abuse

Changes in Bile Acid Concentrations after Administration of Ketoconazole or Rifampicin to Chimeric Mice with Humanized Liver

Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly

Changes in Bile Acid Concentrations in Chimeric Mice Transplanted with Different Replacement Indexes of Human Hepatocytes

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development

Metabolism of Butyrylfentanyl in Fresh Human Hepatocytes: Chemical Synthesis of Authentic Metabolite Standards for Definitive Identification

Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver

PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization

HCV-induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

An Association Between Core Mutations in Hepatitis B Virus Genotype F1b and Hepatocellular Carcinoma in Alaskan Native People

Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection

Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection

Prediction of Human Hepatic Clearance for Cytochrome P450 Substrates via a New Culture Method Using the Collagen Vitrigel Membrane Chamber and Fresh Hepatocytes Isolated from Liver Humanized Mice

第46回 日本毒性学会学術年会でのPXBマウス及びPXB-cells関連研究発表、ランチョンセミナー開催及びブース展示のご案内

EASLでのPXBマウス・PXB-cells関連研究発表のご案内

第15回広島肝臓プロジェクト研究センターシンポジウムでのPXBマウス及びPXBマウス関連研究発表のご案内

第46回日本毒性学会学術年会でのPXBマウス及びPXB-cells関連研究発表、ランチョンセミナー開催及びブース展示のご案内