Mice with Chimeric Human Livers and Their Applications

Douglas, D. N. Kneteman, N. M.

Methods Mol Biol. 2019;1911:459-479.

Propagation of Human Hepatocytes in uPA/SCID Mice: Producing Chimeric Mice with Humanized Liver

Ohshita, H. Tateno, C.

Methods Mol Biol. 2017;1506:91-100. (Book of Hepatocyte Transplantation)

Propagation of Human Hepatocytes in uPA/SCID Mice: Producing Chimeric Mice with Humanized Liver

Ohshita, H. Tateno, C.

Methods Mol Biol. 2017;1506:91-100. (Book of Hepatocyte Transplantation)

Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice

Tateno, C. Kawase, Y. Tobita, Y. Hamamura, S. Ohshita, H. Yokomichi, H. Sanada, H. Kakuni, M. Shiota, A. Kojima, Y. Ishida, Y. Shitara, H. Wada, N. A. Tateishi, H. Sudoh, M. Nagatsuka, S. Jishage, K. Kohara, M.

PLoS One. 2015 Nov 4;10(11):e0142145. doi: 10.1371/journal.pone.0142145. eCollection 2015.

Efficient engraftmentof human iPS cell-derived hepatocyte-like cells in uPA/SCID mice by overexpression of FNK, a Bcl-xmutant gene

Nagamoto, Y. Takayama, K. Tashiro, K. Tateno, C. Sakurai, F. Tachibana, M. Kawabata, K. Ikeda, K. Tanaka, Y. Mizuguchi, H.
Cell Transplant. 2014 May 6.

Transplantation of engineered chimeric liver with autologous hepatocytes and xenobiotic scaffold

Hata T, Uemoto S, Fujimoto Y, Murakami T, Tateno C, Yoshizato K, Kobayashi E.
Ann Surg. 2013 Mar;257(3):542-7.

Morphological and microarray analyses of human hepatocytes from xenogeneic host livers

Chise Tateno, Fuyuki Miya, Kenjiro Wake, Miho Kataoka, Yuji Ishida, Chihiro Yamasaki, Ami Yanagi,　Masakazu Kakuni,　Eddie Wisse, Fons Verheyen, Kouji Inoue, Kota Sato, Atsushi Kudo, Shigeki Arii,　Toshiyuki Itamoto, Toshimasa Asahara, Tatsuhiko Tsunoda and Katsutoshi Yoshizato
Lab Invest. 2013 Jan;93(1):54-71.

Liver tissue engineering utilizing hepatocytes propagated in mouse livers in vivo.

Ohashi K, Tatsumi K, Tateno C, Kataoka M, Utoh R, Yoshizato K, Okano T.
Cell Transplant. 2012;21(2-3):429-36.

Human hepatocyte propagation system in the mouse livers: functional maintenance of the production of coagulation and anticoagulation factors.

Tatsumi K, Ohashi K, Tateno C, Yoshizato K, Yoshioka A, Shima M, Okano T.
Cell Transplant. 2012;21(2-3):437-45.

A novel animal model for in vivo study of liver cancer metastasis.

Fujiwara S, Fujioka H, Tateno C, Taniguchi K, Ito M, Ohishi H, Utoh R, Ishibashi H, Kanematsu T, Yoshizato K.
World J Gastroenterol. 2012 Aug 7;18(29):3875-82.

Growth hormone-dependent pathogenesis of human hepatic steatosis in a novel mouse model bearing a human hepatocyte-repopulated liver.

Tateno C, Kataoka M, Utoh R, Tachibana A, Itamoto T, Asahara T, Miya F, Tsunoda T, Yoshizato K.
Endocrinology. 2011 Apr;152(4):1479-91.

Morphologic characterization of PhoenixBio (uPA+/+/SCID) humanized liver chimeric mouse model.

Peterson RA, Krull DL, Brown HR, de Serres M.

Drug Metab Lett. 2010 Aug;4(3):180-184.

Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice.

Utoh R, Tateno C, Kataoka M, Tachibana A, Masumoto N, Yamasaki C, Shimada T, Itamoto T, Asahara T, Yoshizato K.
Am J Pathol. 2010 177 654-665

In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.

Kubo S, Kataoka M, Tateno C, Yoshizato K, Kawasaki Y, Kimura T, Faure-Kumar E, Palmer DJ, Ng P, Okamura H, Kasahara N.

Hum Gene Ther. 2010 Jan;21(1):40-50.

Successful in vivo propagation of factor IX-producing hepatocytes in mice: Potential for cell-based therapy in haemophilia B.

Tatsumi K, Ohashi K, Kataoka M, Tateno C, Shibata M, Naka H, Shima M, Hisanaga M, Kanehiro H, Okano T, Yoshizato K, Nakajima Y, Yoshioka A.
Thromb Haemost. 2008;99(5):883-891.

Human cord blood cells transplanted into chronically damaged liver exhibit similar characteristics to functional hepatocytes

Kakinuma, S. Asahina, K. Okamura, K. Teramoto, K. Tateno, C. Yoshizato, K. Tanaka, Y. Yasumizu, T. Transplant Proc. 2007 Jan-Feb;39(1):240-3.Sakamoto, N.Watanabe, M. Teraoka, H.

Transplant Proc. 2007 Jan-Feb;39(1):240-243.

GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver

Masumoto N, Tateno C, Tachibana A, Utoh R, Morikawa Y, Shimada T, Momisako H, Itamoto T, Asahara T,
J Endocrinol. 2007 Sep;194(3):529-37.

Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver

Okamura, K. Asahina, K. Fujimori, H. Ozeki, R. Shimizu-Saito, K. Tanaka, Y. Teramoto, K. Arii, S. Takase, K. Kataoka, M. Soeno, Y. Tateno, C. Yoshizato, K. Teraoka, H.

Histochem Cell Biol. 2006 ;125(3):247-257.

Efficient in vivo Xenogeneic retroviral vector-mediated gene transduction into human hepatocytes.

Kentaro Emoto, Chise Tateno, Hiroshi Hino, Hironobu Amano, Yasuhiro Imaoka, Kinji Asahina, Toshimasa Asahara and Katsutoshi Yoshizato

Hum Gene Ther. 2005 Oct; 16: 1168-1174.