Phoenix Bio

研究発表

研究発表

Development and characterization of secondary standards for nucleic acid amplification technology (NAAT) assays for detection of hepatitis E virus

    Fares-Gusmao, R. Jiang, Z. Subramaniam, S. Visser, B. J. Scott, A. Ishida, Y. Saito, T. Baylis, S. A. McGivern, D. R. H. E. V. Standard Calibration Study Group
    J Clin Virol. 2022 Dec;157:105325. doi: 10.1016/j.jcv.2022.105325.

    Functional involvement of endothelial lipase in hepatitis B virus infection

      Shirasaki, T. Murai, K. Ishida, A. Kuroki, K. Kawaguchi, K. Wang, Y. Yamanaka, S. Yasukawa, R. Kawasaki, N. Li, Y. Y. Shimakami, T. Sumiyadorj, A. Nio, K. Sugimoto, S. Orita, N. Takayama, H. Okada, H. Thi Bich, P. D. Iwabuchi, S. Hashimoto, S. Ide, M. Tabata, N. Ito, S. Matsushima, K. Yanagawa, H. Yamashita, T. Kaneko, S. Honda, M.
      Hepatol Commun. 2023 Aug 31;7(9):e0206.

      Function of hepatocyte spheroids in bioactive microcapsules is enhanced by endogenous and exogenous hepatocyte growth factor

        Gwon, K. Choi, D. de Hoyos-Vega, J. M. Baskaran, H. Gonzalez-Suarez, A. M. Lee, S. Hong, H. J. Nguyen, K. M.n Dharmesh, E. Sugahara, G. Ishida, Y. Saito, T. Stybayeva, G. Revzin, A.
        Bioact Mater. 2023 May 24;28:183-195. doi: 10.1016/j.bioactmat.2023.05.009.

        Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes

          Fattahi, P. de Hoyos-Vega, J. M. Choi, J. H. Duffy, C. D. Gonzalez-Suarez, A. M. Ishida, Y. Nguyen, K. M. Gwon, K. Peterson, Q. P. Saito, T. Stybayeva, G. Revzin, A.
          Cells. 2023 Aug 1;12(15):1982. doi: 10.3390/cells12151982.

          Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics

            Hailegiorgis, A. Ishida, Y. Collier, N. Imamura, M. Shi, Z. Reinharz, V. Tsuge, M. Barash, D. Hiraga, N. Yokomichi, H. Tateno, C. Ozik, J. Uprichard, S. L. Chayama, K. Dahari, H.
            PLoS Comput Biol. 2023 Aug 3;19(8):e1011309. doi: 10.1371/journal.pcbi.1011309.

            Super-Resolution Microscopy Analysis of Hepatitis B Viral cccDNA and Host Factors

              Doan, P. T. B. Nio, K. Shimakami, T. Kuroki, K. Li, Y. Y. Sugimoto, S. Takayama, H. Okada, H. Kaneko, S. Honda, M. Yamashita, T.
              Viruses. 2023 May 16;15(5):1178. doi: 10.3390/v15051178.

              Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response

                Chida, T. Ishida, Y. Morioka, S. Sugahara, G. Han, C. Lam, B. Yamasaki, C. Sugahara, R. Li, M. Tanaka, Y. Liang, T. J. Tateno, C. Saito, T.
                JCI Insight. 2023 May 8;8(9):e162404. doi: 10.1172/jci.insight.162404.

                Amentoflavone inhibits hepatitis B virus infection via the suppression of preS1 binding to host cells

                  Aoki-Utsubo, C. Indrasetiawan, P. Fukano, K. Muramatsu, M. Artanti, N. Hanafi, M. Hotta, H. Kameoka, M.
                  Microbiol Immunol. 2023 Mar 16. doi: 10.1111/1348-0421.13064.

                  Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes

                    Edwards, J. S. Delabat, S. A. Badilla, A. D. DiCaprio, R. C. Hyun, J. Burgess, R. A. Silva, T. Dykxhoorn, D. M. Chen, S. X. Wang, L. Ishida, Y. Saito, T. Thomas, E.
                    JHEP Rep. 2022 Sep 23;4(12):100592. doi: 10.1016/j.jhepr.2022.100592. eCollection 2022 Dec.

                    The Gut-Organ-Axis Concept: Advances the Application of Gut-on-Chip Technology

                      Guo, Y. Chen, X. Gong, P.Li, G. Yao, W. Yang, W.
                      Int J Mol Sci. 2023 Feb 17;24(4):4089. doi: 10.3390/ijms24044089.

                      The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides

                        Guo, X Ghosh, A. K. Keyes, R. F. Peterson, F. Forman, M. Meyers, D. J. Arav-Boger, R.
                        Viruses. 2022 Jan 25;14(2):234. doi: 10.3390/v14020234.

                        Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening

                          Primadharsini, P. P. Nagashima, S. Nishiyama, T. Takahashi, M. Murata, K. Okamoto, H.
                          J Virol. 2022 Mar 23;96(6):e0190621. doi: 10.1128/jvi.01906-21. Epub 2022 Feb 2.

                          Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action

                            Toyama, M. Watashi, K. Ikeda, M. Yamashita, A. Okamoto, M. Moriishi, K. Muramatsu, M. Wakita, T. Sharon, A. Baba, M.
                            Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0207321. doi: 10.1128/aac.02073-21. Epub 2022 May 23.

                            Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA

                              Kim, E. S. Zhou, J. Zhang, H. Marchetti, A. van de Klundert, M. Cai, D.Yu, X. Mitra, B. Liu, Y. Wang, M. Protzer, U. Guo, H.
                              PLoS Pathog. 2022 Jun 9;18(6):e1010576. doi: 10.1371/journal.ppat.1010576.

                              Autophagic membranes participate in hepatitis B virus nucleocapsid assembly, precore and core protein trafficking, and viral release

                                Chu, J. Y. K. Chuang, Y. C. Tsai, K. N. Pantuso, J. Ishida, Y. Saito, T. Ou, J. J.

                                Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2201927119. doi: 10.1073/pnas.2201927119. Epub 2022 Jul 18.

                                Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits hepatitis B virus infection and replication

                                  Ide, M. Tabata, N. Yonemura, Y. Shirasaki, T. Murai, K. Wang, Y. Ishida, A. Okada, H. Honda, M. Kaneko, S. Doi, N. Ito, S. Yanagawa, H.
                                  J Biol Chem. 2022 Jul;298(7):102097. doi: 10.1016/j.jbc.2022.102097. Epub 2022 Jun 2.

                                  Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection

                                    Takemori, T. Sugimoto-Ishige, A. Nishitsuji, H. Futamura, Y. Harada, M. Kimura-Someya, T. Matsumoto, T. Honma, T. Tanaka, M. Yaguchi, M. Isono, K. Koseki, H. Osada, H. Miki, D. Saito, T. Tanaka, T. Fukami, T. Goto, T. Shirouzu, M. Shimotohno, K. Chayama, K.
                                    J Virol. 2022 Mar 9;96(5):e0168621. doi: 10.1128/JVI.01686-21. Epub 2022 Jan 5.

                                    Antiviral Compounds Screening Targeting HBx Protein of the Hepatitis B Virus

                                      Ma, Y. Nakamoto, S. Ao, J. Qiang, N. Kogure, T. Ogawa, K. Nakagawa, M. Fujiwara, K. Iwanaga, T. Kojima, R. Kanzaki, H. Koroki, K. Kobayashi, K. Kanogawa, N. Kiyono, S. Nakamura, M. Kondo, T. Nakagawa, R. Ogasawara, S. Muroyama, R. Chiba, T. Kato, J. Kato, N.
                                      Int J Mol Sci. 2022 Oct 10;23(19):12015. doi: 10.3390/ijms231912015.

                                      N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx

                                        Murata, T. Iwahori, S. Okuno, Y. Nishitsuji, H. Yanagi, Y. Watashi, K. Wakita, T. Kimura, H. Shimotohno, K.
                                        Int J Mol Sci. 2023 Jan 23;24(3):2265. doi: 10.3390/ijms24032265.

                                        A Novel Anti-HBV Agent, E-CFCP, restores Hepatitis B virus (HBV)-induced Senescence-associated Cellular Markers Perturbation in Human Hepatocytes

                                          Takamatsu, Y. Hayashi, S. Kumamoto, H. Imoto, S. Tanaka, Y. Mitsuya, H. Higashi-Kuwata, N.
                                          Virus Res. 2023 Mar 23;329:199094. doi: 10.1016/j.virusres.2023.199094.