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GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver

GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver

Masumoto N, Tateno C, Tachibana A, Utoh R, Morikawa Y, Shimada T, Momisako H, Itamoto T, Asahara T,
J Endocrinol. 2007 Sep;194(3):529-37.

Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.

2007/09/01

Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y, Suzuki H.

Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1450-1463.

In Vivo Drug Metabolism Model for Human Cytochrome P450 Enzyme Using Chimeric Mice with Humanized Liver

2007/09/01

Katoh M, Sawada T, Soeno Y, Nakajima M, Tateno C, Yoshizato K, Yokoi T.

J Pharm Sci. 2007 Feb;96(2):428-437.

Evaluation of human hepatocyte chimeric mice as a model for toxicological investigation using panomic approaches–effect of acetaminophen on the expression profiles of proteins and endogenous metabolites in liver, plasma and urine

2007/08/01

Yamamoto T, Tomizawa K, Fujikawa M, Sato Y, Yamada H, Horii I.
J Toxicol Sci. 2007 Aug;32(3):205-15.

Bezafibrate induces multidrug-resistance P-Glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice.

2007/07/01

Shoda J, Okada K, Inada Y, Kusama H, Utsunomiya H, Oda K, Yokoi T, Yoshizato K, Suzuki H.
Hepatol Res. 2007 Jul;37(7):548-56.

Humanization of Excretory Pathway in Chimeric Mice with Humanized Liver

2007/06/01

Okumura H, Katoh M, Sawada T, Nakajima M, Soeno Y, Yabuuchi H, Ikeda T, Tateno C, Yoshizato K, Yokoi T.
Toxicol Sci. 2007 Jun;97(2):533-8. Epub 2007 Mar 6.

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C Virus and its susceptibility to interferon

2007/05/15

Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K.
FEBS Lett. 2007 May 15;581(10):1983-7. Epub 2007 Apr 20.

Early Dynamics of Hepatitis B Virus in Chimeric Mice Carrying Human Hepatocytes Monoinfected or Coinfected with Genotype G

2007/04/01

Sugiyama M, Tanaka Y, Sakamoto T, Maruyama I, Shimada T, Takahashi S, Shirai T, Kato H, Nagao M, Miyakawa Y, Mizokami M.
Hepatology. 2007 Apr;45(4):929-37.

Evaluation of Cyclophilin Inhibitor in Hepatitis C Virus-Infected Chimeric Mice In Vivo

2007/04/01

Inoue K, Umehara T, Ruegg UT, Yasui F, Watanabe T, Yasuda H, Dumont JM, Scalfaro P, Yoshiba M, Kohara M.
Hepatology. 2007 Apr;45(4):921-8.

Humanized mice in translational biomedical research.

2007/02/01

Shultz LD, Ishikawa F, Greiner DL.
Nat Rev Immunol. 2007 Feb;7(2):118-30.

Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

2007/02/01

Nakagawa S, Umehara T, Matsuda C, Kuge S, Sudoh M, Kohara M.
Biochem Biophys Res Commun. 2007 Feb 23;353(4):882-8. Epub 2006 Dec 22.

Application of chimeric mice with humanized liver for predictive adme

2007/01/01

Katoh M, Yokoi T.
Drug Metab Rev. 2007;39(1):145-57.

In Vivo Induction of Human Cytochrome P450 Enzymes Expressed in Chimeric Mice with Humanized Liver

2006/12/20

Katoh M, Matsui T, Nakajima M, Tateno C, Soeno Y, Horie T, Iwasaki K, Yoshizato K, Yokoi T.

Drug Metab Dispos. 2005 Jun;33(6):754-763.

Influence of Hepatitis B Virus Genotypes on the Intra- and Extracellular Expression of Viral DNA and Antigens

2006/09/01

Sugiyama M, Tanaka Y, Kato T, Orito E, Ito K, Acharya SK, Gish RG, Kramvis A, Shimada T, Izumi N, Kaito M, Miyakawa Y, Mizokami M.

Hepatology. 2006 Oct;44(4):915-24.

Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver

2006/09/01

Yoshitsugu H, Nishimura M, Tateno C, Kataoka M, Takahashi E, Soeno Y, Yoshizato K, Yokoi T, Naito S.

Drug Metab Pharmacokinet. 2006;21(6):465-474.

Emergence of a Novel Lamivudine-Resistant Hepatitis B Virus Variant with a Substitution Outside the YMDD Motif

2006/09/01

Yatsuji H, Noguchi C, Hiraga N, Mori N, Tsuge M, Imamura M, Takahashi S, Iwao E, Fujimoto Y, Ochi H, Abe H, Maekawa T, Tateno C, Yoshizato K, Suzuki F, Kumada H, Chayama K.
Antimicrob Agents Chemother. 2006 Nov;50(11):3867-74. Epub 2006 Sep 18.

Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe

2006/09/01

Aoki K, Kashiwagura Y, Horie T, Sato H, Tateno C, Ozawa N, Yoshizato K.

Drug Metab Pharmacokinet. 2006 ;21(4):277-285.

Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model

2006/09/01

Umehara T, Sudoh M, Yasui F, Matsuda C, Hayashi Y, Chayama K, Kohara M.

Biochem Biophys Res Commun. 2006 Jul 21;346(1):67-73. Epub 2006 May 24.

Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver

Okamura, K. Asahina, K. Fujimori, H. Ozeki, R. Shimizu-Saito, K. Tanaka, Y. Teramoto, K. Arii, S. Takase, K. Kataoka, M. Soeno, Y. Tateno, C. Yoshizato, K. Teraoka, H.

Histochem Cell Biol. 2006 ;125(3):247-257.

Embryonic dermal condensation and adult dermal papilla induce hair follicles in adult glabrous epidermis through different mechanisms

2006/02/01

Inamatsu M, Tochio T, Makabe A, Endo T, Oomizu S, Kobayashi E, Yoshizato K.
Dev Growth Differ. 2006 Feb;48(2):73-86.