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PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization

PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization

2019/06/26

Mueller, H. Lopez, A. Tropberger, P. Wildum, S. Schmaler, J. Pedersen, L. Han, X. Wang, Y. Ottosen, S. Yang, S. Young, J. A. T. Javanbakht, H.

Hepatology. 2019 Apr;69(4):1398-1411. doi: 10.1002/hep.30329. Epub 2019 Mar 1.

HCV-induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

2019/06/26

Hamdane, N. Juhling, F. Crouchet, E. El Saghire, H. Thumann, C. Oudot, M. A. Bandiera, S. Saviano, A. Ponsolles, C. Roca Suarez, A. A. Li, S. Fujiwara, N. Ono, A. Davidson, I. Bardeesy, N. Schmidl, C. Bock, C. Schuster, C. Lupberger, J. Habersetzer, F. Doffoel, M. Piardi, T. Sommacale, D. mamura, M. Uchida, T. Ohdan, H. Aikata, H. Chayama, K. Boldanova, T. Pessaux, P. Fuchs, B. C. Hoshida, Y. Zeisel, M. B. Duong, F. H. T. Baumert, T. F.

Gastroenterology. 2019 Mar 2. pii: S0016-5085(19)32506-5. doi: 10.1053/j.gastro.2019.02.038.

An Association Between Core Mutations in Hepatitis B Virus Genotype F1b and Hepatocellular Carcinoma in Alaskan Native People

2019/06/26

Hayashi, S. Khan, A. Simons, B. C. Homan, C. Matsui, T. Ogawa, K. Kawashima, K. Murakami, S. Takahashi, S. Isogawa, M. Ikeo, K. Mizokami, M. McMahon, B. J. Tanaka, Y.

Hepatology. 2019 Jan;69(1):19-33. doi: 10.1002/hep.30111. Epub 2018 Dec 10.

Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection

2019/06/26

Ishida, Y. Kakuni, M. Bang, B. R. Sugahara, G. Lau, D. T. Tateno-Mukaidani, C. Li, M. Gale, M., Jr. Saito, T.

J Interferon Cytokine Res. 2019 Mar;39(3):133-146. doi: 10.1089/jir.2018.0103.

Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection

2019/06/26

Tsuge, M. Uchida, T. Walsh, K. Ishida, Y. Tateno, C. Kumar, U. Glenn, J. S. Koh, C. Heller, T. Uprichard, S. L. Dahari, H. Chayama, K.

Viruses. 2019 Mar 15;11(3). pii: v11030263. doi: 10.3390/v11030263.

Prediction of Human Hepatic Clearance for Cytochrome P450 Substrates via a New Culture Method Using the Collagen Vitrigel Membrane Chamber and Fresh Hepatocytes Isolated from Liver Humanized Mice

2019/06/26

Watari, R. Kakiki, M. Yamasaki, C. Ishida, Y. Tateno, C. Kuroda, Y. Ishida, S. Kusano, K.

Biol Pharm Bull. 2019;42(3):348-353. doi: 10.1248/bpb.b18-00582.

第46回 日本毒性学会学術年会でのPXBマウス及びPXB-cells関連研究発表、ランチョンセミナー開催及びブース展示のご案内

2019/06/17
2019年6月26日(水)~6月28日(金)に開催されます第46回 日本毒性学会学術年会にてPXBマウス及びPXB-cells関連の研究発表、ランチョンセミナー及びブース展示を行います。

EASLでのPXBマウス・PXB-cells関連研究発表のご案内

2019/04/03

4月10日(水)~14日(日)にReed Messe Wien Exhibition & Congress Center(オーストリアのウィーン)で開催されますEASL The International Liver Congress 2019にて、PXBマウス・PXB-cells関連研究発表及びブース展示があります。

Ribonucleotide reductase M2 promotes RNA replication of hepatitis C virus by protecting NS5B protein from hPLIC1-dependent proteasomal degradation

2019/03/20

Kitab, B. Satoh, M. Ohmori, Y. Munakata, T. Sudoh, M. Kohara, M. Tsukiyama-Kohara, K.

J Biol Chem. 2019 Feb 12. pii: RA118.004397. doi: 10.1074/jbc.RA118.004397.

Prediction of human pharmacokinetics of long half-life compounds using chimeric mice with humanised liver

2019/03/20

Miyamoto, M. Iwasaki, S. Chisaki, I. Nakagawa, S. Amano, N. Kosugi, Y. Hirabayashi, H.

Xenobiotica. 2019 Feb 12:1-31. doi: 10.1080/00498254.2019.1579394.

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

2019/03/20

Tsushima, K. Tsuge, M. Hiraga, N. Uchida, T. Murakami, E. Makokha, G. N. Kurihara, M. Nomura, M. Hiyama, Y. Fujino, H. Ono, A. Nakahara, T. Yamauchi, M. Abe-Chayama, H. Kawaoka, T. Miki, D. Imamura, M. Aikata, H. Hayes, C. N. Chayama, K.

J Gastroenterol. 2019 Feb 21. pii: 10.1007/s00535-019-01558-w. doi: 10.1007/s00535-019-01558-w.

MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct

2019/03/20

Jain, R. Frederick, J. P. Huang, E. Y. Burke, K. E. Mauger, D. M. Andrianova, E. A. Farlow, S. J.Siddiqui, S. Pimentel, J. Cheung-Ong, K. McKinney, K. M. Kohrer, C. Moore, M. J. Chakraborty, T.

Nucleic Acid Ther. 2018 Oct;28(5):285-296.

Chimeric mice with human hepatocytes: A new system for genotoxicity studies

2019/03/20

C. Tateno, M. Fukumuro, S. Masumori, M. Kakuni, Y. Ishida, T. Shimada, M. Hayashi

Mutat Res. 2019 Mar;839:9-12

Functional Analysis of Human Hepatocytes Isolated From Chimeric Mouse Liver

2019/03/20

Harimoto, N. Nakagawara, H. Shirabe, K. Yoshizumi, T. Itoh, S. Ikegami, T. Soejima, Y. Maehara, Y. Ishida, Y. Tateno, C. Tanaka, Y.

Transplant Proc. 2018 Dec;50(10):3858-3862. doi: 10.1016/j.transproceed.2018.06.035.

Lack of human relevance for procymidone’s developmental toxicity attributable to species difference in its kinetics and metabolism

2019/03/20

Tomigahara, Y. Tarui, H. Matsui, M. Kurosawa, M. Kawamura, S. Isobe, N.

J Pestic Sci. 2018 May 20;43(2):114-123. doi: 10.1584/jpestics.D17-085.

Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model

2019/03/20

Ye, X. Tateno, C. Thi, E. P. Kakuni, M. Snead, N. M. Ishida, Y. Barnard, T. R. Sofia, M. Shimada, T. Lee, A. C. H.

ACS Infect Dis. 2018 Nov 8. doi: 10.1021/acsinfecdis.8b00192.

ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection

2019/03/20

Thi, E. P. Dhillon, A. P. Ardzinski, A. Bidirici-Ertekin, L. Cobarrubias, K. D. Cuconati, A. Kondratowicz, A. S. Kwak, K. Li, A. H. L. Miller, A. Pasetka, C. Pei, L.Phelps, J. R. Snead, N. M. Wang, X. Ye, X. Sofia, M. J. Lee, A. C. H.

ACS Infect Dis. 2018 Nov 19. doi: 10.1021/acsinfecdis.8b00191.

SOT 58th Annual Meeting and ToxExpo 2019でのPXBマウス・PXB-cells関連研究発表のご案内

2019/03/06

3月10日(日)~14日(木)にBaltimore Convention Center (米国メリーランド州ボルチモア)で開催されますSOT 58th Annual Meeting and ToxExpo 2019にて、PXBマウス・PXB-cells関連研究発表及びブース展示があります。

シンポジウム「細胞アッセイ技術の現状と将来」でのPXBマウス・PXB-cells関連研究発表のご案内

2019/01/23

2019年1月30日(水)に茨城県つくば市の産業技術総合研究所 つくばセンター共用講堂で開催されますシンポジウム「細胞アッセイ技術の現状と将来」にて、PXBマウス・PXB-cells関連研究発表があります。

第1回医薬品毒性機序研究会でのPXBマウス・PXB-cells関連研究発表のご案内(演題追加)

2019/01/16

2019年1月10日(木)~11日(金)に名古屋大学 東山キャンパス 野依記念学術交流会館で開催されました日本毒性学会

第1回医薬品毒性機序研究会にて、PXBマウス・PXB-cells関連研究発表及びブース展示がありました(演題追加)。