2015年 12月6日(日)~12月10日(木)にGrand Wailea(Maui, Hawaii)にて開催されましたHepDART 2015
にてPXBマウスおよびPXB-cells関連研究発表がありましたので、ご案内申し上げます。
“Cyclophilin Inhibitors and Their Potential as Therapeutics for the Treatment of HBV”
Dr. Michael Sofia, Arbutus Biopharma Corporation, USA
“Preclinical and Clinical Profile of NVR 3-778, a First-In-Class HBV Core Inhibitor for the Treatment of Chronic Hepatitis B”
Dr. Osvaldo Flores, Novira Therapeutics, USA
“RG-101, a Novel microRNA Therapeutic to Target the Host Factor of HCV”
Dr. Paul Grint, Regulus Therapeutics, USA
Abstract #110
“4′-Modified Nucleoside Analogs: Potent Inhibitors Active against Entecavir Resistant Hepatitis B Virus (HBV) and their Structure-Activity Relationship”
Dr. Hiroaki Mitsuya, Kumamoto University, Japan
Abstract #111
“BB-HB-331, a DNA-Directed RNA Interference Agent (ddRNAi) for the Treatment of Subjects Infected with the Hepatitis B Virus (HBV), Can Effectively Suppress HBV in a Primary Hepatocyte Model”
Dr. David Suhy, Benitec Biopharma, USA