Lack of exposure in a first-in-man study due to aldehyde oxidase metabolism: Investigated by use of 14C-microdose, humanized mice, monkey pharmacokinetics and in vitro methods 2016/12/14 DMPKPXB-Mouse Jensen, K. G. Jacobsen, A. M. Bundgaard, C. Nilausen, D. O. Thale, Z. Chandrasena, G. Jorgensen, M. Drug Metab Dispos. 2016 Oct 13. pii: dmd.116.072793. BACK Page top