Phoenix Bio

In vitro evaluation of cytochrome p450 and glucuronidation activities in hepatocytes isolated from liver-humanized mice.

In vitro evaluation of cytochrome p450 and glucuronidation activities in hepatocytes isolated from liver-humanized mice.

2011/02/01

Yamasaki C, Kataoka M, Kato Y, Kakuni M, Usuda S, Ohzone Y, Matsuda S, Adachi Y, Ninomiya S, Itamoto T, Asahara T, Yoshizato K, Tateno C.
Drug Metab Pharmacokinet. 2011 Jan 14;25(6):539-50

Morphologic characterization of PhoenixBio (uPA+/+/SCID) humanized liver chimeric mouse model.

Peterson RA, Krull DL, Brown HR, de Serres M.

Drug Metab Lett. 2010 Aug;4(3):180-184.

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.

2011/02/01

Tsuge M, Hiraga N, Akiyama R, Tanaka S, Matsushita M, Mitsui F, Abe H, Kitamura S, Hatakeyama T, Kimura T, Miki D, Mori N, Imamura M, Takahashi S, Hayes CN, Chayama K.

J Gen Virol. 2010 Jul;91(Pt 7):1854-64.

Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants.

2011/02/01

Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M.

Virology. 2010 Sep 30;405(2):361-9.

Positive selection of core 70Q variant genotype 1b hepatitis C virus strains induced by pegylated interferon and ribavirin.

2011/02/01

Kurbanov F, Tanaka Y, Matsuura K, Sugauchi F, Elkady A, Khan A, Hasegawa I, Ohno T, Tokuda H, Mizokami M.

J Infect Dis. 2010 Jun 1;201(11):1663-71

Animal model for study of human hepatitis viruses.

2011/01/13

Chayama K, Hayes CN, Hiraga N, Abe H, Tsuge M, Imamura M.
J Gastroenterol Hepatol. 2011 Jan;26(1):13-8

THE EMERGING ROLE OF PHARMACOGENETICS IN THE TREATMENT OF PATTERNED HAIR LOSS

2011/01/05

Yuha Y Kojima , Akio Sato , and Koh-ei Toyoshima

Hair Transplantation (5Th) _BOOK;Chapter 5: page 97-101.

C型肝炎感染を起こすタンパク質

2011/01/02

中国新聞

Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients

2011/01/01

Yamazaki, M.  Sato, A. Toyoshima, K. E. Kojima, Y. Okada, T. Ishii, Y. Kurata, S. Yoshizato, K. Tsuboi, R.

J Dermatol. 2011 Jul;38(7):680-4.

Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.

2010/12/12

Kamimura H, Nakada N, Suzuki K, Mera A, Souda K, Murakami Y, Tanaka K, Iwatsubo T, Kawamura A, Usui T.

Drug Metab Pharmacokinet. 2010;25(3):223-35.

Effect of hepatitis C virus infection on the mRNA expression of drug transporters and cytochrome p450 enzymes in chimeric mice with humanized liver.

2010/11/01

Kikuchi R, McCown M, Olson P, Tateno C, Morikawa Y, Katoh Y, Bourdet DL, Monshouwer M, Fretland AJ.
Drug Metab Dispos. 2010 Nov;38(11):1954-61.

Contact between Dermal Papilla Cells and Dermal Sheath Cells Enhances the Ability of DPCs to Induce Hair Growth

2010/08/01

Yamao M, Inamatsu M, Ogawa Y, Toki H, Okada T, Toyoshima KE, Yoshizato K.
J Invest Dermatol. 2010 Aug 19.

Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice.

Utoh R, Tateno C, Kataoka M, Tachibana A, Masumoto N, Yamasaki C, Shimada T, Itamoto T, Asahara T, Yoshizato K.
Am J Pathol. 2010 177 654-665

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.

2010/07/01

Kamiya N, Iwao E, Hiraga N, Tsuge M, Imamura M, Takahashi S, Miyoshi S, Tateno C, Yoshizato K, Chayama K.
J Gen Virol. 2010 Jul;91(Pt 7):1668-77. Epub 2010 Feb 17.

In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.

Kubo S, Kataoka M, Tateno C, Yoshizato K, Kawasaki Y, Kimura T, Faure-Kumar E, Palmer DJ, Ng P, Okamura H, Kasahara N.

Hum Gene Ther. 2010 Jan;21(1):40-50.

第16回日本遺伝子治療学会

2010/06/23

第16回日本遺伝子治療学会

日本トキシコロジー学会第37回年会

2010/06/14

第6回広島肝臓プロジェクト研究センターシンポジウム 

2010/06/04

Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver.

2010/05/01

Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
Drug Metab Pharmacokinet. in press.

日本薬学会第130年会 

2010/03/28