Phoenix Bio

Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.

Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.

2010/12/12

Kamimura H, Nakada N, Suzuki K, Mera A, Souda K, Murakami Y, Tanaka K, Iwatsubo T, Kawamura A, Usui T.

Drug Metab Pharmacokinet. 2010;25(3):223-35.

Effect of hepatitis C virus infection on the mRNA expression of drug transporters and cytochrome p450 enzymes in chimeric mice with humanized liver.

2010/11/01

Kikuchi R, McCown M, Olson P, Tateno C, Morikawa Y, Katoh Y, Bourdet DL, Monshouwer M, Fretland AJ.
Drug Metab Dispos. 2010 Nov;38(11):1954-61.

Contact between Dermal Papilla Cells and Dermal Sheath Cells Enhances the Ability of DPCs to Induce Hair Growth

2010/08/01

Yamao M, Inamatsu M, Ogawa Y, Toki H, Okada T, Toyoshima KE, Yoshizato K.
J Invest Dermatol. 2010 Aug 19.

Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice.

Utoh R, Tateno C, Kataoka M, Tachibana A, Masumoto N, Yamasaki C, Shimada T, Itamoto T, Asahara T, Yoshizato K.
Am J Pathol. 2010 177 654-665

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.

2010/07/01

Kamiya N, Iwao E, Hiraga N, Tsuge M, Imamura M, Takahashi S, Miyoshi S, Tateno C, Yoshizato K, Chayama K.
J Gen Virol. 2010 Jul;91(Pt 7):1668-77. Epub 2010 Feb 17.

In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.

Kubo S, Kataoka M, Tateno C, Yoshizato K, Kawasaki Y, Kimura T, Faure-Kumar E, Palmer DJ, Ng P, Okamura H, Kasahara N.

Hum Gene Ther. 2010 Jan;21(1):40-50.

第16回日本遺伝子治療学会

2010/06/23

第16回日本遺伝子治療学会

日本トキシコロジー学会第37回年会

2010/06/14

第6回広島肝臓プロジェクト研究センターシンポジウム 

2010/06/04

Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver.

2010/05/01

Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
Drug Metab Pharmacokinet. in press.

日本薬学会第130年会 

2010/03/28

ヒト型肝臓を持つキメラマウスから分離したヒト肝細胞のCYPおよびUGT活性の評価

2010/02/10

Yamasaki, C., et al

DMPK. 2010; 6:45

ヒト肝細胞キメラマウスを用いた治療抵抗性の肝炎に関する研究

2010/01/02

茶山一彰

研究班会議

ヒト肝細胞キメラマウス

2010/01/02

立野知世

総合臨床 2010; 59(2): 297-298

Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry.

2010/01/01

Yamazaki H, Kuribayashi S, Inoue T, Tateno C, Nishikura Y, Oofusa K, Harada D, Naito S, Horie T, Ohta S.
Chem Res Toxicol. 2010 Jan;23(1):152-8.

In vivo modeling of human liver for pharmacological study using humanized mouse.

2009/12/12

Yoshizato K, Tateno C.

Expert Opin Drug Metab Toxicol. 2009 Nov;5(11):1435-46.

第57回 日本ウイルス学会学術年会

2009/10/25

Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.

2009/09/23

Hiraga N, Imamura M, Hatakeyama T, Kitamura S, Mitsui F, Tanaka S, Tsuge M, Takahashi S, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Wakita T, Chayama K.
J Hepatol. 2009 Dec;51(6):1046-54. Epub 2009 Sep 23.

A human hepatocyte-bearing mouse: an animal model to predict drug metabolism and effectiveness in humans.

2009/08/12

Yoshizato K, Tateno C.

PPAR Res.2009:476217. Epub 2009 Oct 26.

Amphipathic DNA polymers inhibit hepatitis C virus infection by blocking viral entry.

2009/08/01

Matsumura T, Hu Z, Kato T, Dreux M, Zhang YY, Imamura M, Hiraga N, Juteau JM, Cosset FL, Chayama K, Vaillant A, Liang TJ.
Gastroenterology. 2009 Aug;137(2):673-81