Phoenix Bio

研究発表

研究発表

In Vivo Induction of Human Cytochrome P450 Enzymes Expressed in Chimeric Mice with Humanized Liver

    Katoh M, Matsui T, Nakajima M, Tateno C, Soeno Y, Horie T, Iwasaki K, Yoshizato K, Yokoi T.

    Drug Metab Dispos. 2005 Jun;33(6):754-763.

    Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver

      Yoshitsugu H, Nishimura M, Tateno C, Kataoka M, Takahashi E, Soeno Y, Yoshizato K, Yokoi T, Naito S.

      Drug Metab Pharmacokinet. 2006;21(6):465-474.

      Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe

        Aoki K, Kashiwagura Y, Horie T, Sato H, Tateno C, Ozawa N, Yoshizato K.

        Drug Metab Pharmacokinet. 2006 ;21(4):277-285.

        Induction of Human CYP1A2 and CYP3A4 in Primary Culture of Hepatocytes from Chimeric Mice with Humanized Liver

          Nishimura M, Yokoi T, Tateno C, Kataoka M, Takahashi E, Horie T, Yoshizato K, Naito S.

          Drug Metab Pharmacokinet. 2005;20(2):121-126.

          Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver

            Nishimura M, Yoshitsugu H, Yokoi T, Tateno C, Kataoka M, Horie T, Yoshizato K, Naito S.

            Xenobiotica. 2005 Sep;35(9):877-890.

            In vivo induction of human cytochrome P450 3A4 by rifabutin in chimeric mice with humanized liver

              Katoh M, Watanabe M, Tabata T, Sato Y, Nakajima M, Nishimura M, Naito S, Tateno C, Iwasaki K, Yoshizato K, Yokoi T.

              Xenobiotica. 2005 Sep;35(9):863-875.

              Expression of Human Phase Ⅱ Enzymes in Chimeric Mice with Humanized Liver

                Katoh M, Matsui T, Okumura H, Nakajima M, Nishimura M, Naito S, Tateno C, Yoshizato K, Yokoi T.

                Drug Metab Dispos. 2005 Sep;33(9):1333-1340.

                Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs

                  Tateno C, Yoshizane Y, Saito N, Kataoka M, Utoh R, Yamasaki C, Tachibana A, Soeno Y, Asahina K, Hino H, Asahara T, Yokoi T, Furukawa T, Yoshizato K.

                  Am J Pathol. 2004 Sep;165(3):901-912.

                  Expression of Human Cytochromes P450 in Chimeric Mice with Humanized Liver

                    Katoh M, Matsui T, Nakajima M, Tateno C, Kataoka M, Soeno Y, Horie T, Iwasaki K, Yoshizato K, Yokoi T.

                    Drug Metab Dispos. 2004 Dec;32(12):1402-1410.