Phoenix Bio

論文一覧

論文一覧

論文一覧

HBV感染キメラマウスモデル

杉山真也、田中靖人、溝上雅史

細胞:(特集 ヒト細胞キメラマウスの医学・薬学利用)2008;40(1):13-16

HCV感染キメラマウスモデル

今村道雄、平賀伸彦、茶山一彰

細胞:(特集 ヒト細胞キメラマウスの医学・薬学利用)2008;40(1):9-12

キメラマウスの薬物動態

加藤 美紀、 横井 毅

細胞:(特集 ヒト細胞キメラマウスの医学・薬学利用)2008;40(1):5-8

ヒト肝細胞キメラマウスの開発とその利用

立野知世

細胞:(特集 ヒト細胞キメラマウスの医学・薬学利用)2008;40(1):2-4

Correlation between Polymorphic CAG-Repeats in the Androgen-Receptor Gene and Therapeutic Efficiency of Finasteride in Androgenetic Alopecia

 Sato A, Arima Y, Kojima Y, Toyoshima K, Okada T, Ishii Y, Kurata S, Yoshizato K.

Skin Surgegry. 2008; 17(2): 80-86.

ヒト肝細胞キメラマウスの医薬品開発への応用

加国雅和、立野知世

MINOPHAGEN MEDICAL REVIEW 2008; 53: 1-13

Single lymphocyte analysis with a microwell array chip.

    Tokimitsu Y, Kishi H, Kondo S, Honda R, Tajiri K, Motoki K, Ozawa T, Kadowaki S, Obata T, Fujiki S, Tateno C, Takaishi H, Chayama K, Yoshizato K, Tamiya E, Sugiyama T, Muraguchi A.
    Cytometry A, 2007 Dec;71(12):1003-10.

    Human cord blood cells transplanted into chronically damaged liver exhibit similar characteristics to functional hepatocytes

      Kakinuma, S. Asahina, K. Okamura, K. Teramoto, K. Tateno, C. Yoshizato, K. Tanaka, Y. Yasumizu, T. Transplant Proc. 2007 Jan-Feb;39(1):240-3.Sakamoto, N.Watanabe, M. Teraoka, H.

      Transplant Proc. 2007 Jan-Feb;39(1):240-243.

      GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver

        Masumoto N, Tateno C, Tachibana A, Utoh R, Morikawa Y, Shimada T, Momisako H, Itamoto T, Asahara T,
        J Endocrinol. 2007 Sep;194(3):529-37.

        Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.

          Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y, Suzuki H.

          Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1450-1463.

          In Vivo Drug Metabolism Model for Human Cytochrome P450 Enzyme Using Chimeric Mice with Humanized Liver

            Katoh M, Sawada T, Soeno Y, Nakajima M, Tateno C, Yoshizato K, Yokoi T.

            J Pharm Sci. 2007 Feb;96(2):428-437.

            Evaluation of human hepatocyte chimeric mice as a model for toxicological investigation using panomic approaches–effect of acetaminophen on the expression profiles of proteins and endogenous metabolites in liver, plasma and urine

              Yamamoto T, Tomizawa K, Fujikawa M, Sato Y, Yamada H, Horii I.
              J Toxicol Sci. 2007 Aug;32(3):205-15.

              Bezafibrate induces multidrug-resistance P-Glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice.

                Shoda J, Okada K, Inada Y, Kusama H, Utsunomiya H, Oda K, Yokoi T, Yoshizato K, Suzuki H.
                Hepatol Res. 2007 Jul;37(7):548-56.

                Humanization of Excretory Pathway in Chimeric Mice with Humanized Liver

                  Okumura H, Katoh M, Sawada T, Nakajima M, Soeno Y, Yabuuchi H, Ikeda T, Tateno C, Yoshizato K, Yokoi T.
                  Toxicol Sci. 2007 Jun;97(2):533-8. Epub 2007 Mar 6.

                  Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C Virus and its susceptibility to interferon

                    Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K.
                    FEBS Lett. 2007 May 15;581(10):1983-7. Epub 2007 Apr 20.

                    Early Dynamics of Hepatitis B Virus in Chimeric Mice Carrying Human Hepatocytes Monoinfected or Coinfected with Genotype G

                      Sugiyama M, Tanaka Y, Sakamoto T, Maruyama I, Shimada T, Takahashi S, Shirai T, Kato H, Nagao M, Miyakawa Y, Mizokami M.
                      Hepatology. 2007 Apr;45(4):929-37.

                      Evaluation of Cyclophilin Inhibitor in Hepatitis C Virus-Infected Chimeric Mice In Vivo

                        Inoue K, Umehara T, Ruegg UT, Yasui F, Watanabe T, Yasuda H, Dumont JM, Scalfaro P, Yoshiba M, Kohara M.
                        Hepatology. 2007 Apr;45(4):921-8.

                        Humanized mice in translational biomedical research.

                          Shultz LD, Ishikawa F, Greiner DL.
                          Nat Rev Immunol. 2007 Feb;7(2):118-30.

                          Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

                            Nakagawa S, Umehara T, Matsuda C, Kuge S, Sudoh M, Kohara M.
                            Biochem Biophys Res Commun. 2007 Feb 23;353(4):882-8. Epub 2006 Dec 22.

                            Application of chimeric mice with humanized liver for predictive adme

                              Katoh M, Yokoi T.
                              Drug Metab Rev. 2007;39(1):145-57.