Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/21245155

Yuen MF, Wong DK, Lee CK, Tanaka Y, Allain JP, Fung J, Leung J, Lin CK, Sugiyama M, Sugauchi F, Mizokami M, Lai CL.
Clin Infect Dis. 2011 Mar;52(5):624-32

Cross-species transmission of gibbon and orangutan hepatitis B virus to uPA/SCID mice with human hepatocytes.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/21510984

Sa-Nguanmoo P, Tanaka Y, Ratanakorn P, Sugiyama M, Murakami S, Payungporn S, Sommanustweechai A, Mizokami M, Poovorawan Y.
Virus Res. 2011 Jun;158(1-2):209-15

PBXマウス由来新鮮肝細胞を用いたインビトロ代謝試験

安達弥長

HAB Newsleter 2011; 18(1): 21-23

In vitro evaluation of cytochrome p450 and glucuronidation activities in hepatocytes isolated from liver-humanized mice.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20930422

Yamasaki C, Kataoka M, Kato Y, Kakuni M, Usuda S, Ohzone Y, Matsuda S, Adachi Y, Ninomiya S, Itamoto T, Asahara T, Yoshizato K, Tateno C.
Drug Metab Pharmacokinet. 2011 Jan 14;25(6):539-50

Morphologic characterization of PhoenixBio (uPA+/+/SCID) humanized liver chimeric mouse model.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20642451

Peterson RA, Krull DL, Brown HR, de Serres M.

Drug Metab Lett. 2010 Aug;4(3):180-184.

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20219897

Tsuge M, Hiraga N, Akiyama R, Tanaka S, Matsushita M, Mitsui F, Abe H, Kitamura S, Hatakeyama T, Kimura T, Miki D, Mori N, Imamura M, Takahashi S, Hayes CN, Chayama K.

J Gen Virol. 2010 Jul;91(Pt 7):1854-64.

Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20609455

Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M.

Virology. 2010 Sep 30;405(2):361-9.

Positive selection of core 70Q variant genotype 1b hepatitis C virus strains induced by pegylated interferon and ribavirin.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20420509

Kurbanov F, Tanaka Y, Matsuura K, Sugauchi F, Elkady A, Khan A, Hasegawa I, Ohno T, Tokuda H, Mizokami M.

J Infect Dis. 2010 Jun 1;201(11):1663-71

Animal model for study of human hepatitis viruses.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/21175788

Chayama K, Hayes CN, Hiraga N, Abe H, Tsuge M, Imamura M.
J Gastroenterol Hepatol. 2011 Jan;26(1):13-8

THE EMERGING ROLE OF PHARMACOGENETICS IN THE TREATMENT OF PATTERNED HAIR LOSS

Yuha Y Kojima , Akio Sato , and Koh-ei Toyoshima

Hair Transplantation (5Th) _BOOK;Chapter 5: page 97-101.

Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/21352305

Yamazaki, M.  Sato, A. Toyoshima, K. E. Kojima, Y. Okada, T. Ishii, Y. Kurata, S. Yoshizato, K. Tsuboi, R.

J Dermatol. 2011 Jul;38(7):680-4.

Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20610881

Kamimura H, Nakada N, Suzuki K, Mera A, Souda K, Murakami Y, Tanaka K, Iwatsubo T, Kawamura A, Usui T.

Drug Metab Pharmacokinet. 2010;25(3):223-35.

Effect of hepatitis C virus infection on the mRNA expression of drug transporters and cytochrome p450 enzymes in chimeric mice with humanized liver.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed?term=20693416

Kikuchi R, McCown M, Olson P, Tateno C, Morikawa Y, Katoh Y, Bourdet DL, Monshouwer M, Fretland AJ.
Drug Metab Dispos. 2010 Nov;38(11):1954-61.

Contact between Dermal Papilla Cells and Dermal Sheath Cells Enhances the Ability of DPCs to Induce Hair Growth

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20720567

Yamao M, Inamatsu M, Ogawa Y, Toki H, Okada T, Toyoshima KE, Yoshizato K.
J Invest Dermatol. 2010 Aug 19.

Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20522646

Utoh R, Tateno C, Kataoka M, Tachibana A, Masumoto N, Yamasaki C, Shimada T, Itamoto T, Asahara T, Yoshizato K.
Am J Pathol. 2010 177 654-665

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/20164258

Kamiya N, Iwao E, Hiraga N, Tsuge M, Imamura M, Takahashi S, Miyoshi S, Tateno C, Yoshizato K, Chayama K.
J Gen Virol. 2010 Jul;91(Pt 7):1668-77. Epub 2010 Feb 17.

In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/19725756

Kubo S, Kataoka M, Tateno C, Yoshizato K, Kawasaki Y, Kimura T, Faure-Kumar E, Palmer DJ, Ng P, Okamura H, Kasahara N.

Hum Gene Ther. 2010 Jan;21(1):40-50.

Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver.

Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
Drug Metab Pharmacokinet. in press.

ヒト型肝臓を持つキメラマウスから分離したヒト肝細胞のCYPおよびUGT活性の評価

Yamasaki, C., et al

DMPK. 2010; 6:45

Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry.

• Pub Med URL http://www.ncbi.nlm.nih.gov/pubmed/19928966

Yamazaki H, Kuribayashi S, Inoue T, Tateno C, Nishikura Y, Oofusa K, Harada D, Naito S, Horie T, Ohta S.
Chem Res Toxicol. 2010 Jan;23(1):152-8.