Identification of glycogen synthase kinase 3alpha/beta as a host factor required for HBV transcription using high-throughput screening

2025/05/08

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39847392/

Nishitsuji, H. Naito, Y. Murakami, Y. Sugiyama, M. Mizokami, M. Shoji, I. Murata, T. Shimotohno, K.
Hepatology. 2025 Jan 23. doi: 10.1097/HEP.0000000000001239.

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Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/40048440

Nosaka, T. Naito, T. Akazawa, Y. Takahashi, K. Matsuda, H. Ohtani, M. Nishizawa, T. Okamoto, H. Nakamoto, Y.
PLoS One. 2025 Mar 6;20(3):e0314581. doi: 10.1371/journal.pone.0314581.

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Quantitative prediction of drug disposition for uridine diphosphate-glucuronosyltransferase substrates using humanized mice

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/40054035

Miyake, T. Fujita, Y. Hirabayashi, M. Komiyama, N. Morita, K. Tachibana, T. Terao, K.
Drug Metab Dispos. 2025 Feb 10;53(4):100050. doi: 10.1016/j.dmd.2025.100050.

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Development of human growth hormone-treated chimeric mice with humanized livers for an evaluation model of drug-induced fatty liver disease

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39979474

Morioka, S. Sanoh, S. Ishida, Y. Furukawa, S. Ogawa, Y.Kotake, Y. Tateno, C.
Arch Toxicol. 2025 Feb 21. doi: 10.1007/s00204-025-03986-5.

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Investigation of Biotransformation Pathways in a Chimeric Mouse with a Humanized Liver

2025/05/08

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39940909/

Karlsson, I. B. Ekdahl, A. Etchingham-Coll, H. Li, X. Q. Ericsson, C. Ahlqvist, M. Samuelsson, K.
Int J Mol Sci. 2025 Jan 28;26(3):1141. doi: 10.3390/ijms26031141

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Endothelial lipase-binding peptides similar to netrin-1 inhibit hepatitis B virus infection

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39865491

Ide, M. Tabata, N. Murai, K. Yonemura, Y. Wang, Y. Ishida, A. Shirasaki, T. Kaneko, S. Ito, S. Honda, M. Yanagawa, H.
FEBS Lett. 2025 Jan 25. doi: 10.1002/1873-3468.15101.

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Induction of phospholipase A2 group 4C by HCV infection regulates lipid droplet formation

2025/05/08

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39802806/

Ito, M. Liu, J. Fukasawa, M. Tsutsumi, K. Kanegae, Y. Setou, M. Kohara, M. Suzuki, T.
JHEP Rep. 2024 Sep 30;7(1):101225. doi: 10.1016/j.jhepr.2024.101225.

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Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene

2025/05/08

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39787208/

Zhang, M. Mouzannar, K. Zhang, Z. Teraoka, Y. Piotrowski, J. Ishida, Y. Tateno-Mukaidani, C. Saito, T.Abe-Chayama, H. Chayama, K.Liang, T. J.
PLoS Pathog. 2025 Jan 9;21(1):e1012803. doi: 10.1371/journal.ppat.1012803.

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Theoretical modeling of hepatitis C acute infection in liver-humanized mice support pre-clinical assessment of candidate viruses for controlled-human-infection studies

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39738554

Shi, Z. Mhlanga, A. Ishida, Y. Josephson, A. Collier, N. T. Abe-Chayama, H. Tateno-Mukaidani, C. Cotler, S. J. Ozik, J. Major, M. Feld, J. J. Chayama, K. Dahari, H.
Sci Rep. 2024 Dec 30;14(1):31826. doi: 10.1038/s41598-024-83104-0.

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Alteration of Gene Expression After Entecavir and Pegylated Interferon Therapy in HBV-Infected Chimeric Mouse Liver

2025/05/08

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39599858

Bao, H. Murakami, S. Tsuge, M. Uchida, T. Uchikawa, S. Fujino, H. Ono, A. Murakami, E. Kawaoka, T. Miki, D. Hayes, C. N. Oka, S.
Viruses. 2024 Nov 6;16(11):1743. doi: 10.3390/v16111743.

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Modelling of hepatitis B virus kinetics and accumulation of cccDNA in primary human hepatocytes

2025/05/08

Pub Med URL https://doi.org/10.1016/j.jhepr.2024.101311

Louis Shekhtman, Yuji Ishida, Masataka Tsuge, Vladimir Reinharz, Mikaru Yamao, Masaki Takahashi, Chise Tateno, Susan L. Uprichard, Harel Dahari, Kazuaki Chayama
JHEP Reports https://doi.org/10.1016/j.jhepr.2024.101311.

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An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection

2024/11/06

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39209804/

Mukherji, A. Jühling, F. Simanjuntak, Y. Crouchet, E. Del Zompo, F. Teraoka, Y. Haller, A. Baltzinger, P. Paritala, S. Rasha, F. Fujiwara, N. Gadenne, C. Slovic, N. Oudot, M. A. Durand, S. C.
Nat Commun. 2024 Aug 29;15(1):7486. doi: 10.1038/s41467-024-51698-8.

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Plasma and urinary CP I and CP III concentrations in chimeric mice with human hepatocytes after rifampicin administration

2024/11/06

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39312270

Shishido, Y. Yoshida, T. Oshida, K. Uchida, M.
Pharmacol Res Perspect. 2024 Oct;12(5):e70017. doi: 10.1002/prp2.70017.

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Infectivity of Hepatitis B Virus Surface Antigen-Positive Plasma With Undetectable HBV-DNA: Can HBsAg Screening Be Discontinued in Egyptian Blood Donors?

2024/11/06

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39126258

El Ekiaby, M. Tanaka, J. van Drimmelen, H. Allain, J. P. Lelie, N.
J Viral Hepat. 2024 Aug 10. doi: 10.1111/jvh.13990.

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Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice

2024/11/06

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/39168375

Duehren, S. Uchida, T. Tsuge, M. Hiraga, N. Uprichard, S. L. Etzion, O. Glenn, J. Koh, C. Heller, T. Cotler, S. J. Oka, S. Chayama, K. Dahari, H.
Virus Res. 2024 Aug 26;349:199451. doi: 10.1016/j.virusres.2024.199451.

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The Evaluation of Lipid Analysis for PXB-Cells LA as a Human Non-Alcoholic Fatty Liver Disease Model

2024/11/06

Pub Med URL https://www.jstage.jst.go.jp/article/bpbreports/7/4/7_147/_article

Takahashi, Masaki Tomatsu, Sayaka Inamatsu, Mutsumi, Yoshikawa, Nami, Hata, Keishi, Kakuni, Masakazu
BPB Reports (2024) 7(4):147-156

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Lipid nanoparticle-encapsulated DOCK11-siRNA efficiently reduces hepatitis B virus cccDNA level in infected mice

2024/11/06

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39109217/

Okada, H. Sakamoto, T. Nio, K. Li, Y. Kuroki, K. Sugimoto, S. Shimakami, T. Doi, N. Honda, M. Seiki, M. Kaneko, S. Yamashita, T.
Mol Ther Methods Clin Dev. 2024 Jun 24;32(3):101289. doi: 10.1016/j.omtm.2024.101289.

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Human Hepatocytes Can Give Rise to Intrahepatic Cholangiocarcinomas

2024/11/06

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/38866344/

Hsu, Bernadette Y. Driscoll, Julia. Tateno, Chise. Mattis, Aras N. Kelley, Robin K. Willenbring, Holger
Gastroenterology. 2024 Oct;167(5):1029-1032.e7. doi: 10.1053/j.gastro.2024.05.033.

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Utility of Chimeric Mice with Humanized Livers for Predicting Hepatic Organic Anion – Transporting Polypeptide 1B (OATP1B) – Mediated Clinical Drug-Drug Interactions

2024/11/06

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/39103225/

Feng, B. Liang, G. Zetterberg, C. Li, S. Huang, H. Williams, J.Gao, H. Morikawa, Y. Kumar, S.
Drug Metab Dispos. 2024 Aug 5:DMD-AR-2024-001792. doi: 10.1124/dmd.124.001792.

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Selective depletion of HBV-infected hepatocytes by class A capsid assembly modulators requires high levels of intrahepatic HBV core protein

2024/11/06

Pub Med URL https://pubmed.ncbi.nlm.nih.gov/38780261/

Kornyeyev, D. Song, Z. Eng, S. Soulette, C. Ramirez, R. Tang, J. Yue, Q. Subramanian, R. Zaboli, S. Moon, C. Tam, J. Brodbeck, J. Aggarwal, A. Diehl, L. Fletcher, S. P. Hyrina, A. Holdorf, M. M. Burdette, D.
Antimicrob Agents Chemother. 2024 Jul 9;68(7):e0042024. doi: 10.1128/aac.00420-24.

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