株式会社フェニックスバイオ

Inhibitory effect of silibinin on hepatitis B virus entry

2018/11/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29872730

Umetsu, T. Inoue, J. Kogure, T. Kakazu, E. Ninomiya, M. Iwata, T. Takai, S. Nakamura, T.Sano, A. Shimosegawa, T.

Biochem Biophys Rep. 2018 Mar 31;14:20-25.

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A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers

2018/11/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30078838

Watari, R. Kakiki, M. Oshikata, A. Takezawa, T. Yamasaki, C. Ishida, Y. Tateno, C. Kuroda, Y. Ishida, S. Kusano, K.

J Toxicol Sci. 2018;43(8):521-529.

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Inhibitory effect of Japanese rice-koji miso extracts on hepatitis A virus replication in association with the elevation of glucose-regulated protein 78 expression

2018/11/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/30123052

Win, N. N. Kanda, T. Nakamoto, S. Moriyama, M. Jiang, X. Suganami, A. Tamura, Y. Okamoto, H. Shirasawa, H.

Int J Med Sci. 2018 Jul 30;15(11):1153-1159.

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新規ready-to-use ヒト肝細胞三次元培養システム「PXB-able」の有用性の検討

2018/08/14

Pub Med URL http://mol.medicalonline.jp/archive/search?jo=ao8bioib&ye=2018&vo=35&issue=3

赤平有希、山崎ちひろ、石田雄二、立野知世、城村友子

BIO-INDUSTRY 2018;35（3）：27-37

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Contribution of chimeric mice with a humanized liver to the evaluation of pharmacology, toxicity, and pharmacokinetics in drug discovery and development

2018/08/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29760366

Sanoh, S. Ohta, S.

Nihon Yakurigaku Zasshi. 2018;151(5):213-220

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Use of hepatocytes isolated from a liver-humanized mouse for studies on the metabolism of drugs: application to the metabolism of fentanyl and acetylfentanyl

2018/08/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29963210

Kanamori, T. Togawa-Iwata, Y. Segawa, H. Yamamuro, T. Kuwayama, K. Tsujikawa, K. Inoue, H.

Forensic Toxicol. 2018;36(2):467-475.

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Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

2018/08/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29916799

Teraoka, Y. Uchida, T. Imamura, M. Hiraga, N. Osawa, M. Kan, H. Saito, Y. Tsuge, M. Abe-Chayama, H. Hayes, C. N. Makokha, G. N. Aikata, H. Miki, D. Ochi, H. Ishida, Y. Tateno, C. Chayama, K.

J Gen Virol. 2018 Jun 19. doi: 10.1099/jgv.0.001091.

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Generation of the Adenovirus Vector-Mediated CRISPR/Cpf1 System and the Application for Primary Human Hepatocytes Prepared from Humanized Mice with Chimeric Liver

2018/08/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29962404

Tsukamoto, T. Sakai, E. Iizuka, S. Taracena-Gandara, M. Sakurai, F. Mizuguchi, H.

Biol Pharm Bull. 2018;41(7):1089-1095. doi: 10.1248/bpb.b18-00222.

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The whole transcriptome effects of the PPARalpha agonist fenofibrate on livers of hepatocyte humanized mice

2018/08/14

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29879903

de la Rosa Rodriguez, M. A. Sugahara, G. Hooiveld, Gjej Ishida, Y. Tateno, C. Kersten, S.

BMC Genomics. 2018 Jun 7;19(1):443. doi: 10.1186/s12864-018-4834-3.

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Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discovery

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29183653

Naritomi, Y. Sanoh, S. Ohta, S.

Drug Metab Pharmacokinet. 2017 Nov 9. pii: S1347-4367(17)30150-7. doi: 10.1016/j.dmpk.2017.11.001.

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Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/28368357

Livingston, C. M. Ramakrishnan, D. Strubin, M. Fletcher, S. P. Beran, R. K.

Viruses. 2017 Apr 3;9(4). pii: E69. doi: 10.3390/v9040069.

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Propagation of Human Hepatocytes in uPA/SCID Mice: Producing Chimeric Mice with Humanized Liver

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/27830547

Ohshita, H. Tateno, C.

Methods Mol Biol. 2017;1506:91-100. (Book of Hepatocyte Transplantation)

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Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29621544

Teraoka, Y. Uchida, T. Imamura, M. Osawa, M. Tsuge, M. Abe-Chayama, H. Hayes, C. N. Makokha, G. N. Aikata, H. Miki, D. Ochi, H. Ishida, Y. Tateno, C. Chayama, K.

Biochem Biophys Res Commun. 2018 Jun 2;500(2):152-157.

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Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactions

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29678521

Takaoka, N. Sanoh, S. Okuda, K. Kotake, Y. Sugahara, G. Yanagi, A. Ishida, Y. Tateno, C. Tayama, Y. Sugihara, K. Kitamura, S. Kurosaki, M. Terao, M. Garattini, E. Ohta, S.

Biochem Pharmacol. 2018 Apr 17;154:28-38.

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FXR Activation by Obeticholic Acid or Non-Steroidal Agonists Induces a Human-Like Lipoprotein Cholesterol Change in Mice with Humanized Chimeric Liver

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29559521

Papazyan, R. Liu, X. Liu, J. Dong, B. Plummer, E. M. Lewis, R. D., 2nd Roth, J. D. Young, M. A.

J Lipid Res. 2018 Mar 20. pii: jlr.M081935. doi: 10.1194/jlr.M081935.

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Acute HBV infection in humanized chimeric mice has multiphasic viral kinetics

2018/05/22

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29572897

Ishida, Y. Chung, T. L. Imamura, M. Hiraga, N. Sen, S. Yokomichi, H. Tateno, C. Canini, L. Perelson, A. S. Uprichard, S. L. Dahari, H. Chayama, K.

Hepatology. 2018 Mar 23. doi: 10.1002/hep.29891.

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Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

2018/03/12

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29373739

Rolt, A. Le, D. Hu, Z. Wang, A. Q. Shah, P. Singleton, M. Hughes, E. Dulcey, A. E.He, S. Imamura, M. Uchida, T. Chayama, K. Xu, X. Marugan, J. J. Liang, T. J.

J Infect Dis. 2018 Jan 24. pii: 4823490. doi: 10.1093/infdis/jiy039.

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A natural small molecule inhibitor corilagin blocks HCV replication and modulates oxidative stress to reduce liver damage

2018/03/12

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29224736

Reddy, B. U. Mullick, R. Kumar, A. Sharma, G. Bag, P. Roy, C. L. Sudha, G. Tandon, H. Dave, P. Shukla, A. Srinivasan, P. Nandhitha, M.Srinivasan, N. Das, S.

Antiviral Res. 2017 Dec 7;150:47-59.

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Investigating the hepatitis B virus life cycle using engineered reporter hepatitis B viruses

2018/03/12

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/29121422

Nishitsuji, H. Harada, K. Ujino, S. Zhang, J. Kohara, M. Sugiyama, M. Mizokami, M. Shimotohno, K.

Cancer Sci. 2018 Jan;109(1):241-249.

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Hepatitis C replication inhibitors that target the viral NS4B protein

2018/03/12

Pub Med URL https://www.ncbi.nlm.nih.gov/pubmed/23544424

Miller, J. F. Chong, P. Y. Shotwell, J. B. Catalano, J. G. Tai, V. W. Fang, J. Banka, A. L. Roberts, C. D. Youngman, M. Zhang, H. Xiong, Z. Mathis, A. Pouliot, J. J. Hamatake, R. K. Price, D. J. Seal, J. W., 3rd Stroup, L. L. Creech, K. L. Carballo, L. H. Todd, D. Spaltenstein, A. Furst, S. Hong, Z. Peat, A. J.

J Med Chem. 2014 Mar 13;57(5):2107-20

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